Tuesday, January 31, 2012

BTG's varicose-vein drug succeeds in U.S. study (Reuters)

LONDON (Reuters) ? British pharmaceutical firm BTG said the first of two U.S. trials of its varicose vein treatment Varisolve had met all its goals, bringing a launch of the long-delayed product a step closer.

Varisolve is a ground-breaking treatment that uses an injectable foam to dissolve the veins as an alternative to removing them surgically. The company has forecast peak sales of between $250 million and $500 million if it is approved.

Its development, however, received a major setback in 2003 when regulators in the United States halted a trial of the drug over concerns about side effects of the foam and its active agent Polidocanol entering the bloodstream.

BTG said the final-stage, Phase III trial showed significant benefits on all end points and no major safety concerns, such as stroke or pulmonary emboli, for the 590 patients in the entire program.

Shares in BTG, which have gained 15 percent in the last three months, were 3.7 percent higher at 335.5 pence by 4:41 a.m. ET, the top performer in the mid-cap index.

Analysts at Deutsche Bank said the results of the trial significantly reduced the risks of the regulatory process for the drug.

Overall success rates for Varisolve were expected to be in line with prior clinical data, in the mid 80s percent, they said.

"This combined with benefits on ease of use, speed, lower pain and likely reduced treatment cost should make Varisolve a highly competitive option vs alternatives," they said.

Jefferies said the results bode well for future Varisolve data, but it remained cautious on the treatment's commercial potential and regulatory risks.

"We believe lingering safety concerns could ultimately preclude FDA approval, although we do not expect a decision until at least second half of 2013," the broker said.

"If BTG is able to secure approval, we believe the competitive varicose vein market, in addition to pricing and reimbursement difficulties, could limit future sales and we forecast only $100m at peak."

Chief Executive Louise Makin said the results of a second study would follow, and the group was on track to submit an application to U.S. regulators by the end of the year.

BTG, which also sells niche anti-poison treatments, decided in 2010 to market Varisolve itself in the United States rather than sharing development costs with a partner.

($1 = 0.6383 British pounds)

(Editing by Sarah Young and Erica Billingham)

Source: http://us.rd.yahoo.com/dailynews/rss/meds/*http%3A//news.yahoo.com/s/nm/20120130/hl_nm/us_btg

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Study Looks at Possible HIV Drugs-Birth Defect Link (HealthDay)

MONDAY, Jan. 30 (HealthDay News) -- Pregnant women with HIV can prevent passing the AIDS-causing virus to their babies by taking antiretroviral drugs, but there remains a possibility that some of these medications might cause birth defects, such as cleft lip and palate, according to a new study.

Antiretroviral drugs have been found to reduce the risk of mothers passing HIV on to their children from between 15 and 25 percent to less than 1 percent. These drugs, however, are still under investigation and not considered safe during pregnancy, the study authors noted.

To analyze the possible association between antiretroviral drugs and birth defects, Vassiliki Cartsos, an associate professor and director of graduate orthodontics at Tufts University School of Dental Medicine in Boston, and colleagues examined five years of adverse events compiled by the U.S. Food and Drug Administration.

Their findings are published in the January issue of Cleft Palate--Craniofacial Journal.

The investigators found seven antiretroviral drugs were associated with 26 incidents of cleft lip and palate. However, the authors noted, uncovering an association does not prove a cause-and-effect relationship.

In other words, although the study findings should serve as a red flag, the researchers pointed out that the findings do not confirm that the antiretroviral drugs caused the birth defects.

Those drugs included lamivudine (Epivir); efavirenz (known as EFV); nelfinavir (Viracept); and the combination of abacavir (Ziagen), sulfate, lamivudine and zidovudine (Retrovir).

The study authors concluded in a journal news release that more research is needed to determine if there is a link between antiretroviral drugs and cleft lip and palate, a congenital malformation believed to have several causes, including genetic and environmental factors.

More information

The World Health Organization has more about antiretroviral therapy.

Source: http://us.rd.yahoo.com/dailynews/rss/meds/*http%3A//news.yahoo.com/s/hsn/20120131/hl_hsn/studylooksatpossiblehivdrugsbirthdefectlink

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Monday, January 30, 2012

Sexual healing? Not likely

Monday, January 30, 2012

A new study shows the production of sperm is more biologically taxing than previously thought, and expending energy on it has significant health implications.

In research published in PLoS ONE, Dr Damian Dowling of Monash University's School of Biological Sciences and Professor Leigh Simmons of the University of Western Australia have investigated the trade-off between sperm quality and immunity.

The researchers used the Australian cricket, Teleogryllus oceanicus to prove that the production of quality sperm is expensive and males are strategic about investing energy in the biological process.

Dr Dowling said investigations into life history trade-offs - investment in reproduction versus future reproduction and survival prospects - have historically focused on females.

"This study challenges the traditional view that sex, and sperm production, come cheaply to males. It is typically thought that females must invest heavily into reproduction, whereas males can freely produce millions of high-quality, tiny sperm on demand, with few costs," Dr Dowling said.

"Here we show that the costs are in fact large, and these costs dictate how much effort a male will devote into any given sexual encounter."

The crickets were housed either with sexually immature females, sexually mature females incapable of reproduction, or sexually mature females capable of reproduction. Sperm quality was measured twice and immune function once during the experiment.

Dr Dowling said the male crickets were more likely to produce high quality sperm when housed with sexually mature females with whom they could mate, indicating a strategic investment of energy.

The researchers also found that production of quality sperm appeared to have a negative effect on the crickets' immune systems.

"Males that invested heavily in their sperm paid the price of being more likely to succumb to a bacterial infection. And we are not talking about STDs here - we are talking about how increased investment into the quality of the ejaculate corresponds with general reductions in immune function," Dr Dowling said.

###

Monash University: http://www.monash.edu.au

Thanks to Monash University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 79 time(s).

Source: http://www.labspaces.net/117174/Sexual_healing__Not_likely

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Ex-soldier behind Papua New Guinea mutiny arrested

(AP) ? A retired colonel who attempted to take over Papua New Guinea's military and ordered the prime minister to step down has been arrested and charged with mutiny.

Police spokesman Dominic Kakas said Yaura Sasa was arrested Saturday night in a suburb of Port Moresby, the capital. A court spokesman said Sasa was charged with mutiny and appeared in court Sunday.

Sasa led a small group of soldiers in a mutiny Thursday in which the military's top commander was briefly held under house arrest. The mutiny was part of a power struggle in which Prime Minister Peter O'Neill and former Prime Minister Michael Somare claim to be the rightful leader of the South Pacific nation.

Sasa demanded that O'Neill step down within a week to make way for Somare, who appointed Sasa defense chief after being removed from office.

Kakas said the soldiers who followed Sasa had not been arrested.

Parliament replaced Somare with O'Neill in August while Somare was getting medical treatment outside the country. Papua New Guinea's Supreme Court sided with Somare last month, but O'Neill continues to have support from lawmakers.

Somare issued a statement Sunday repeating his call to be reinstated, and calling on police and the military to join him.

Associated Press

Source: http://hosted2.ap.org/apdefault/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-01-28-AS-Papua-New-Guinea-Mutiny/id-a4d0e5defa0d4273826b5736dcdc1248

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Sunday, January 29, 2012

Kevin White Dead: Former Boston Mayor Dies At 82

Kevin White Dead

This file photograph shows former Boston Mayor Kevin White outside Faneuil Hall in Boston on Wednesday, Nov. 1, 2006. Former Mayor Kevin H. White, who led the city for 16 years including racially turbulent times in the 1970s, died Friday, a family spokesman said. He was 82. (AP Photo/Elise Amendola)

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-01-24-People-Demi%20Moore/id-ceece60d40834e19b7fa45a351a805d6

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Amid scandal, revered PSU coach Joe Paterno dies

FILE - In this Oct. 22, 2011 file photo, Penn State coach Joe Paterno stands on the field before his team's NCAA college football game against Northwestern, in Evanston, Ill. Paterno's doctors say that the former Penn State coach's condition has become "serious," following complications from lung cancer in recent days. (AP Photo/Jim Prisching, File)

FILE - In this Oct. 22, 2011 file photo, Penn State coach Joe Paterno stands on the field before his team's NCAA college football game against Northwestern, in Evanston, Ill. Paterno's doctors say that the former Penn State coach's condition has become "serious," following complications from lung cancer in recent days. (AP Photo/Jim Prisching, File)

Laura Scott, of State College, Pa., places a rose at the foot of a statue of Joe Paterno outside Beaver Stadium on the Penn State University campus after learning of his death Sunday, Jan. 22, 2012, in State College,Pa. (AP Photo/Gene J. Puskar)

Members of the Penn State basketball team pause before going out onto the court for an NCAA college basketball game against Indiana, Sunday, Jan. 22, 2012, in Bloomington, Ind. Former Penn State football coach Joe Paterno died Sunday morning the family said in a statement. (AP Photo/Darron Cummings)

People gather around a statue of Joe Paterno outside Beaver Stadium on the Penn State University campus after learning of his death Sunday, Jan. 22, 2012 in State College,Pa. (AP Photo/Gene J. Puskar)

FILE - In this Jan. 1, 1983 file photo, Penn State head football coach Joe Paterno takes a victory ride from his players after defeating Georgia 27-23 in the Sugar Bowl NCAA college football game at the Supderdome in New Orleans, to win the national championship. On Sunday, Jan. 22, 2012, family says Paterno, winningest coach in major college football, has died. (AP Photo/File)

(AP) ? Happy Valley was perfect for Joe Paterno, a place where "JoePa" knew best, where he not only won more football games than any other major college coach, but won them the right way: with integrity and sportsmanship. A place where character came first, championships second.

Behind it all, however, was an ugly secret that ran counter to everything the revered coach stood for.

Paterno, a sainted figure at Penn State for almost half a century but scarred forever by the child sex abuse scandal that led to his stunning dismissal, died Sunday at age 85.

His death came just 65 days after his son Scott said his father had been diagnosed with a treatable form of lung cancer. The cancer was found during a follow-up visit for a bronchial illness. A few weeks later, Paterno broke his pelvis after a fall but did not need surgery.

Mount Nittany Medical Center said in a statement that Paterno died at 9:25 a.m. of "metastatic small cell carcinoma of the lung." Metastatic indicates an illness that has spread from one part of the body to an unrelated area.

The hospital says Paterno was surrounded by family members, who have requested privacy.

Paterno had been in the hospital since Jan. 13 for observation after what his family called minor complications from his cancer treatments. Not long before that, he conducted his only interview since losing his job, with The Washington Post. Paterno was described as frail then, speaking mostly in a whisper and wearing a wig. The second half of the two-day interview was conducted at his bedside.

His family released a statement Sunday morning to announce his death: "His loss leaves a void in our lives that will never be filled."

"He died as he lived," the statement said. "He fought hard until the end, stayed positive, thought only of others and constantly reminded everyone of how blessed his life had been. His ambitions were far reaching, but he never believed he had to leave this Happy Valley to achieve them. He was a man devoted to his family, his university, his players and his community."

Paterno's death just under three months following his last victory called to mind another coaching great, Alabama's Paul "Bear" Bryant, who died less than a month after retiring.

"Quit coaching?" Bryant said late in his career. "I'd croak in a week."

Paterno alluded to the remark made by his friend and rival, saying in 2003: "There isn't anything in my life anymore except my family and my football. I think about it all the time."

Two police officers were stationed to block traffic on the street where Paterno's modest ranch home stands next to a local park. The officers said the family had asked there be no public gathering outside the house, still decorated with a Christmas wreath, so Paterno's relatives could grieve privately. And, indeed, the street was quiet on a cold winter day.

Paterno's sons, Scott and Jay, arrived separately at the house late Sunday morning. Jay Paterno, who served as his father's quarterbacks coach, was crying.

Paterno built a program based on the credo of "Success with Honor," and he found both. The man known as "JoePa" won 409 games and took the Nittany Lions to 37 bowl games and two national championships. More than 250 of the players he coached went on to the NFL.

"He will go down as the greatest football coach in the history of the game," Ohio State coach Urban Meyer said after his former team, the Florida Gators, beat Penn State 37-24 in the 2011 Outback Bowl.

Paterno roamed the sidelines for 46 seasons, his thick-rimmed glasses, windbreaker and jet-black sneakers as familiar as the Nittany Lions' blue and white uniforms.

The reputation he built looked even more impressive because he insisted that on-field success not come at the expense of high graduation rates.

But in the middle of his 46th season, the legend was shattered. Paterno was engulfed in a child sex abuse scandal when a former trusted assistant, Jerry Sandusky, was accused of molesting 10 boys over a 15-year span, sometimes in the football building.

Outrage built quickly when the state's top cop said the coach hadn't fulfilled a moral obligation to go to the authorities when a graduate assistant, Mike McQueary, told Paterno he saw Sandusky with a young boy in the showers of the football complex in 2002.

At a preliminary hearing for the school officials, McQueary testified that he had seen Sandusky attacking the child with his hands around the boy's waist but said he wasn't 100 percent sure it was intercourse. McQueary described Paterno as shocked and saddened and said the coach told him he had "done the right thing" by reporting the encounter.

Paterno waited a day before alerting school officials and never went to the police.

"I didn't know which way to go ... and rather than get in there and make a mistake," Paterno said in the Post interview.

"You know, (McQueary) didn't want to get specific," Paterno said. "And to be frank with you I don't know that it would have done any good, because I never heard of, of, rape and a man. So I just did what I thought was best. I talked to people that I thought would be, if there was a problem, that would be following up on it."

When the scandal erupted in November, Paterno said he would retire following the 2011 season. He also said he was "absolutely devastated" by the abuse case.

"This is a tragedy," he said. "It is one of the great sorrows of my life. With the benefit of hindsight, I wish I had done more."

But the university trustees fired Paterno, effective immediately. Graham Spanier, one of the longest-serving university presidents in the nation, also was fired.

Paterno was notified by phone, not in person, a decision that board vice chairman John Surma regretted, trustees said. Lanny Davis, the attorney retained by trustees as an adviser, said Surma intended to extend his regrets over the phone before Paterno hung up him.

After weeks of escalating criticism by some former players and alumni about a lack of transparency trustees last week said they fired Paterno in part because he failed a moral obligation to do more in reporting the 2002 allegation.

An attorney for Paterno on Thursday called the board's comments self-serving and unsupported by the facts. Paterno fully reported what he knew to the people responsible for campus investigations, lawyer Wick Sollers said.

"He did what he thought was right with the information he had at the time," Sollers said.

The university handed the football team to one of Paterno's assistants, Tom Bradley, who said Paterno "will go down in history as one of the greatest men, who maybe most of you know as a great football coach."

"As the last 61 years have shown, Joe made an incredible impact," said the statement from the family. "That impact has been felt and appreciated by our family in the form of thousands of letters and well wishes along with countless acts of kindness from people whose lives he touched. It is evident also in the thousands of successful student athletes who have gone on to multiply that impact as they spread out across the country."

New Penn State football coach Bill O'Brien, hired earlier this month, offered his condolences.

"The Penn State Football program is one of college football's iconic programs because it was led by an icon in the coaching profession in Joe Paterno," O'Brien said in a statement. "There are no words to express my respect for him as a man and as a coach. To be following in his footsteps at Penn State is an honor. Our families, our football program, our university and all of college football have suffered a great loss, and we will be eternally grateful for Coach Paterno's immeasurable contributions."

Paterno believed success was not measured entirely on the field. From his idealistic early days, he had implemented what he called a "grand experiment" ? to graduate more players while maintaining success on the field.

"He maintained a high standard in a very difficult profession. Joe preached toughness, hard work and clean competition," Sandusky said in a statement. "Most importantly, he had the courage to practice what he preached."

Paterno was a frequent speaker on ethics in sports, a conscience for a world often infiltrated by scandal.

The team consistently ranked among the best in the Big Ten for graduating players. As of 2011, it had 49 academic All-Americans, the third-highest among schools in the Football Bowl Subdivision. All but two played under Paterno.

"He teaches us about really just growing up and being a man," former linebacker Paul Posluszny, now with the NFL's Jacksonville Jaguars, once said. "Besides the football, he's preparing us to be good men in life."

Paterno certainly had detractors. One former Penn State professor called his high-minded words on academics a farce, and a former administrator said players often got special treatment. His coaching style often was considered too conservative. Some thought he held on to his job too long, and a move to push him out in 2004 failed.

But the critics were in the minority, and his program was never cited for major NCAA violations. The child sex abuse scandal, however, did prompt separate inquiries by the U.S. Department of Education and the NCAA into the school's handling.

Paterno played quarterback and defensive back for Brown University and set a defensive record with 14 career interceptions, a distinction he still boasted about to his teams in his 80s. He graduated in 1950 with plans to go to law school. He said his father hoped he would someday be president.

But when Paterno was 23, a former coach at Brown was moving to Penn State to become the head coach and persuaded Paterno to come with him as an assistant.

"I had no intention to coach when I got out of Brown," Paterno said in 2007 in an interview at Penn State's Beaver Stadium before being inducted into college football's Hall of Fame. "Come to this hick town? From Brooklyn?"

In 1963, he was offered a job by the late Al Davis ? $18,000, triple his salary at Penn State, plus a car to become general manager and coach of the AFL's Oakland Raiders. He said no. Rip Engle retired as Penn State head coach three years later, and Paterno took over.

At the time, Penn State was considered "Eastern football" ? inferior ? and Paterno courted newspaper coverage to raise the team's profile. In 1967, PSU began a 30-0-1 streak.

But Penn State couldn't get to the top of the polls. The Nittany Lions finished second in 1968 and 1969 despite perfect seasons. They were undefeated and untied again in 1973 at 12-0 again but finished fifth. Texas edged them in 1969 after President Richard Nixon, impressed with the Longhorns' bowl performance, declared them No. 1.

"I'd like to know," Paterno said later, "how could the president know so little about Watergate in 1973, and so much about college football in 1969?"

A national title finally came in 1982, after a 27-23 win over Georgia at the Sugar Bowl. Another followed in 1986 after the Lions intercepted Vinny Testaverde five times and beat Miami 14-10 in the Fiesta Bowl.

They made several title runs after that, including a 2005 run to the Orange Bowl and an 11-1 season in 2008 that ended in a 37-23 loss to Southern California in the Rose Bowl.

In his later years, physical ailments wore the old coach down.

Paterno was run over on the sideline during a game at Wisconsin in November 2006 and underwent knee surgery. He hurt his hip in 2008 demonstrating an onside kick. An intestinal illness and a bad reaction to antibiotics prescribed for dental work slowed him for most of the 2010 season. He began scaling back his speaking engagements that year, ending his summer caravan of speeches to alumni across the state.

Then a receiver bowled over Paterno at practice in August, sending him to the hospital with shoulder and pelvis injuries and consigning him to coach much of what would be his last season from the press box.

"The fact that we've won a lot of games is that the good Lord kept me healthy, not because I'm better than anybody else," Paterno said two days before he won his 409th game and passed Eddie Robinson of Grambling State for the most in Division I. "It's because I've been around a lot longer than anybody else."

Paterno could be conservative on the field, especially in big games, relying on the tried-and-true formula of defense, the running game and field position.

He and his wife, Sue, raised five children in State College. Anybody could telephone him at his home ? the same one he appeared in front of on the night he was fired ? by looking up "Paterno, Joseph V." in the phone book.

He walked to home games and was greeted and wished good luck by fans on the street. Former players paraded through his living room for the chance to say hello. But for the most part, he stayed out of the spotlight.

Paterno did have a knack for jokes. He referred to Twitter, the social media site, as "Twittle-do, Twittle-dee."

He also could be abrasive and stubborn, and he had his share of run-ins with his bosses or administrators. And as his legend grew, so did the attention to his on-field decisions, and the questions about when he would hang it up.

Calls for his retirement reached a crescendo in 2004. The next year, Penn State went 11-1 and won the Big Ten. In the Orange Bowl, PSU beat Florida State, whose coach, Bobby Bowden, was eased out after the 2009 season after 34 years and 389 wins.

Like many others, he was outlasted by "JoePa."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-01-22-Obit-Joe%20Paterno/id-03a1fdbba36f4bdcb5089ad4d3ae356a

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Monday, January 23, 2012

Steven Tyler screeches the National Anthem (Reuters)

LOS ANGELES (TheWrap.com) ? Here's the big question, of course: Would "American Idol" judge Steven Tyler have gotten through to the next round?

Judging by the audience reaction that could be heard during his performance of "The Star Spangled Banner" before Sunday's AFC Championship game -- were those really boos for the Aerosmith legend? -- maybe not.

Tyler's rendition was off-key in places, screechy in most others and he messed up a lyric -- it's "the bombs bursting in air," not "as bomb bursting in air." Though he does get rock star fashion points for the festive scarf he was sporting to support his team, the AFC champion New England Patriots.

You can check out video of the performance at the link below and decide: would you give Tyler a golden ticket to Hollywood based on his national anthem performance?

http://www.thewrap.com/media/article/steven-tyler-screeches-national-anthem-video-34672

(Editing by Chris Michaud)

Source: http://us.rd.yahoo.com/dailynews/rss/tv/*http%3A//news.yahoo.com/s/nm/20120123/tv_nm/us_steventyler

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With MegaUpload Down, Who?s Next? RapidShare? SoundCloud? DropBox?

careEvery digital locker service and file linking website is on notice now that MegaUpload and TVShack are down. The Feds have their banhammer out and aren't afraid to use it. Sites better check their zettabytes of data. A single 50 Cent song can cause the Feds to swarm the founder's house and seize their Predator statues. Forget SOPA and PIPA, apparently the US Federal Government doesn't need new legislation in place to shut down major file storage sites and lock millions of users out of their file lockers. The bigger question, then, is who's next? It's clear that the US Federal Government is ramping up its fight against illegal file sharing and hosting. It's the new war on drugs. The plan is to have taxpayers foot the bill and then attack websites rather than regulating or encouraging innovation. The only thing missing is a C.A.R.E. (Computer Abuse Reinforcement Education) presentation at your kids' grade school. Just say no to perfectly legal data sinks, everyone.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/SSbqfCrrl-o/

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Saturday, January 21, 2012

Theresa Shaver: The White Ribbon Alliance: 10 Years In

Picture this: a world where childbirth is the biggest killer of young, healthy women. A world where many girls and women have no choice about who they marry, or how many babies they have or when.

This is how it was when we began the White Ribbon Alliance a little more than a decade ago. In those days, the scandal of maternal and newborn death was scarcely known or acknowledged, especially in Western countries. While struggling to fix the problem from afar, the voices of those women most at risk in the poorest countries -- and those on the ground trying to save them -- were rarely heard.

The White Ribbon Alliance decided to do things differently.

Why not work globally and collectively, we said.

Starting at the grassroots, we brought together those who cared. To listen. To share. To take action.

We called on the big U.N. agencies and small charities, business people and journalists, health professionals and government officials, all over the world to add their voices in a groundswell of demand for change.

We chose the white ribbon as the emblem to unite us; white representing death in some cultures, hope in others. We became a growing band of volunteers, taking time out of our day jobs to connect with each other and figure out how to share scarce resources and open the doors to change.

India led the way in 2002 with the first White Ribbon Alliance march to the Taj Mahal, an iconic memorial to the Shah's young wife who died in childbirth centuries ago. The march attracted thousands of supporters, celebrities, ordinary women, health workers -- and the media, including CNN. The government of India began to listen. Policies were changed to allow nurses in India's half a million villages to perform life-saving procedures. In time, women won the right to free health care in childbirth. The death rates began to go down.

Africa learned from India. One midwife from Tanzania heard what was happening and went to Delhi to find out more. She came back to found the White Ribbon Alliance of Tanzania.

Less than a decade later there are 4,000 members in Tanzania alone, including WHO, Save the Children, UNICEF, the Nurses and Midwives Association, as well as hundreds of smaller groups and thousands of committed individuals. The President of Tanzania himself now joins every march on White Ribbon Day, and the government has changed its policies to train more midwives and give them jobs. The maternal death rate is dropping.

Ten years down the line White Ribbon Alliance has more than 20,000 members in 155 countries, and there are established National Alliances in 15 countries. Sarah Brown is our Global Patron, hugely contributing to the surge in political will for change.

This has led to unprecedented U.N. commitments of $40 billion in 2010, which have risen to $70 billion in 2011. And globally, we are seeing a significant decline in maternal death rates -- a one third reduction since 1990.

And yet we still have a long way to go. Childbirth remains the biggest killer of young women around the world. In sub-Saharan Africa, half of women are still giving birth with only a family member or neighbor to help.

For the world still has less than one health worker for every thousand people. In India alone, over a million newborns die each year -- most from preventable causes -- while globally the figure is 4 million babies dying in the first month of life.

The $70 billion recently pledged by the U.N. is only half of what's needed -- and we have to push hard to make sure these pledges are delivered and spent where it will make the biggest difference. That means investing in the training of health workers, and giving them decent pay and conditions, so that they will stay in their jobs -- and take good care of mothers and babies.

A century ago, more women died in childbirth than men died in wars around the world. Starting in the 1930's, with advances in medicine and political will from governments of wealthier countries, the tide began to turn, so that dying in childbirth is now largely seen as a 'thing of the past' in countries like the U.S. and U.K.

So, we do know what to do and how to save women's lives; we just need the investment and political commitment to do it, for every woman, no matter where she lives.

The White Ribbon Alliance is pushing hard to make this happen.

Please make a donation and share this blog post with friends; together we can make needless deaths in childbirth a thing of the past.

?

Source: http://www.huffingtonpost.com/theresa-shaver/white-ribbon-alliance_b_1213877.html

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ktcmex: @chochesosa B-Sides: A Social Media Story #bsides Feb. 23th, 2012 - Mexico City http://t.co/yHmEE7YI Are You In?

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Source: http://twitter.com/ktcmex/statuses/159691810841702401

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Friday, January 20, 2012

What Things Do You Own That You Could Get Rid Of? [Ask The Readers]

What Things Do You Own That You Could Get Rid Of?Chances are you own an item or twenty that you don't actually need. You may even benefit from parting with that stuff. So in the spirit of not-quite-Spring cleaning, what possessions do you believe deserve a goodbye?

Photo by Tesla Aldrich.

Paul Michael, writing for personal finance blog Wise Bread, came up with a list of 25 items he believes you can toss. Here are a few from the list:

  1. Contents of the junk drawer
  2. Clothing and shoes you haven't worn in the last 12-18 months
  3. Unread books
  4. Expired medicines and Vitamins
  5. (Orphaned) power cords
  6. Spices (they generally only last a couple of years)
  7. Old underwear, socks, and bras
  8. Dated technology, including old cellphones
  9. Perfumes and colognes

What sorts of things do you think you could stand to part with to keep your home a little less cluttered? Let us know in the comments.

25 Things to Throw Out Today | Wise Bread

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/ddCdvl3AVLQ/what-things-do-you-own-that-you-could-get-rid-of

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Exclusive 'The Raid' Clip Will Make You Tired Just Watching It

If you've heard anything about "The Raid," you've probably heard all the right things. Whenever the Indonesian martial arts film has screened, including Midnight Madness at the Toronto International Film Festival, it has left rave reviews in its wake.
We have an exclusive clip from "The Raid" called "Four-On-One," and it's called that for a [...]

Source: http://moviesblog.mtv.com/2012/01/19/the-raid-exclusive-clip/

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Thursday, January 19, 2012

Blood test on mother detects fetus's sex at five weeks

A NON-INVASIVE method of detecting a fetus's sex as early as five weeks into pregnancy has been developed.

Knowing the sex of a fetus is important when the mother is a carrier of an X-chromosome gene that can cause a disease such as muscular dystrophy. In this case, a female fetus will be free of the gene or be a carrier, but a male has a 50 per cent risk of inheriting the disease. In these cases, parents may choose to abort the pregnancy or undergo further, invasive testing, which carries a small risk of miscarriage.

Currently in the UK, for example, women can choose invasive testing at 11 weeks, or wait longer for ultrasound identification of sex. Attempts to analyse fetal DNA in the mother's blood for markers of the male-only Y chromosome can give inaccurate results if not enough DNA is available.

To tackle this problem, Hyun Mee Ryu and colleagues at Cheil General Hospital and Women's Healthcare Center in Seoul, South Korea, measured changes on the PDE9A gene that occur in the blood of a pregnant woman. They then worked out the amount of PDE9A changes that were needed to ensure enough fetal DNA was present to accurately identify whether a Y chromosome was present.

In 203 women, the combination of tests faultlessly detected gender as early as five weeks into pregnancy (The FASEB Journal, DOI: 10.1096/fj.11-191429).

If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.

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Source: http://feeds.newscientist.com/c/749/f/10897/s/1be578fc/l/0L0Snewscientist0N0Carticle0Cmg213284750B30A0A0Eblood0Etest0Eon0Emother0Edetects0Efetuss0Esex0Eat0Efive0Eweeks0Bhtml0DDCMP0FOTC0Erss0Gnsref0Fonline0Enews/story01.htm

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ASUS Transformer Prime OTA rolling out, brings new GPS software version

Prime

The ASUS Transformer Prime is getting another OTA this evening, and reports say that the GPS is working much better.  If you recall, there has been issues surrounding the aluminum casing and GPS signal with the Prime, and ASUS was said to be investigating.  We've confirmed that there's a new build version number (IML74K.US_epad-9.4.2.11-20120117) as well as an update to the GPS software bringing it to version 6.9.13, but there's no official changelog just yet.  If you're rocking a Prime and haven't rooted it, now would be a good time to check for an update from the About Tablet screen.

Thanks, MexDroid!



Source: http://feedproxy.google.com/~r/androidcentral/~3/1lbVrM1an-g/story01.htm

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Wednesday, January 18, 2012

Federer, Nadal smooth over talk of rift

Switzerland's Roger Federer answers questions during a press conference at the Australian Open tennis championship in Melbourne, Australia, Saturday, Jan. 14, 2012. (AP Photo/Sarah Ivey)

Switzerland's Roger Federer answers questions during a press conference at the Australian Open tennis championship in Melbourne, Australia, Saturday, Jan. 14, 2012. (AP Photo/Sarah Ivey)

CORRECTS MISSPELLING OF RUSSIAN PLAYER'S FAMILY NAME - Russia's Nikolay Davydenko reacts to the chair umpire during his first round match against Italy's Flavio Cipolla at the Australian Open tennis championship, in Melbourne, Australia, Monday, Jan. 16, 2012. (AP Photo/Sarah Ivey)

Spain's Rafael Nadal waves to the crowd following his first round match against Alex Kuznetsov of the US at the Australian Open tennis championship, in Melbourne, Australia, Monday, Jan. 16, 2012. (AP Photo/Rick Rycroft)

Spain's Rafael Nadal waves to the crowd following his first round match against Alex Kuznetsov of the US at the Australian Open tennis championship, in Melbourne, Australia, Monday, Jan. 16, 2012. (AP Photo/Rick Rycroft)

Spain's Rafael Nadal waves to the crowd following his first round match against Alex Kuznetsov of the US at the Australian Open tennis championship, in Melbourne, Australia, Monday, Jan. 16, 2012. (AP Photo/Rick Rycroft)

(AP) ? A day after a rare show of discord, Roger Federer and Rafael Nadal quickly closed ranks.

Nadal had criticized Federer for his unwillingness to speak out on issues affecting the men's game, allowing others to "burn themselves" as they seek improved conditions for players.

After joining Nadal in the second round of the Australian Open with a win on Monday, Federer said "things are fine" between the two longtime rivals, although he concedes that they disagree on a way to resolve a list of player grievances that includes the length of the season and the distribution of prize money.

"We can't always agree on everything," Federer said. "So far it's always been no problem really. Back in the day he (Nadal) used to say, 'Whatever Roger decides, I'm fine with.'

"Today he's much more grown up. He has a strong opinion himself, which I think is great."

For his part, Nadal apologized for airing his disagreement with Federer in public ? although he didn't back down on the views he expressed.

"Probably I am wrong telling that to (the media), especially because these things can stay, must stay in the locker room," Nadal said.

"I always had fantastic relationship with Roger. I still have fantastic relationship with Roger. Just I said we can have different views about how the tour needs to work. That's all."

The rift emerged following a player meeting on Saturday that sparked talk of a possible strike for the second time in six months.

Nadal wasn't alone in questioning Federer's stance. Former No. 3-ranked Nikolay Davydenko said Monday he didn't understand why the 16-time Grand Slam champion wasn't supporting his fellow players.

The Russian said that while Nadal and No. 1-ranked Novak Djokovic had been leading the push for changes, Federer had been reluctant to get involved.

"I don't know why Roger is not supporting the players," Davydenko said. "Because he don't want ... any problems. He's nice guy. He's winning Grand Slams. He's from Switzerland. He's perfect.

"He don't want to do anything, he just try to be an outsider from this one."

However, Federer said his reluctance to speak out shouldn't be construed as a lack of support.

"I was in the meeting. I completely understand and support the players' opinions," Federer said. "I just have a different way of going at it. I'm not discussing it with you guys in the press room. It creates unfortunately sometimes negative stories."

The players plan to meet again at the Indian Wells Masters tournament in March when they will assess how much progress has been made before deciding on a course of action.

Davydenko said a strike remained a remote prospect, but that "the ATP should try to do something between now and Indian Wells." Federer wants to avoid such drastic action if possible.

"(Strike) is such a dangerous word to use," Federer said. "It's not good for anyone really. We've seen it in other sports happening in the States. That's why I'm always very careful about it.

"If there's no avoiding it, I'll support the rest of the players. But I just think we have to think it through how we do it, if we do it, can we do it, whatever it is, instead of just going out and screaming about it."

Federer said there are "two or three" big issues that the players have been discussing. They include the length of the season and prize money at Grand Slam tournaments, which some players believe has not increased proportionately with growing profits.

American John Isner said he had been to the meeting and felt the players had a "legitimate beef" over prize money, which is also an issue at the Indian Wells tournament, where Davydenko said those players who lose in the first round can sometimes lose money after paying tax and travel costs to compete.

Federer said he was confident "a good solution" would be reached and he welcomed the healthy debate. Nadal, meanwhile, vowed that he wouldn't be speaking about it in public again.

"I do not talk anymore," he said. "Yesterday (Sunday), I started, and I say I don't want to talk anymore about this. Finally I talked too much as usual. That's not going to happen again. You can try hard, but I'm going to talk about tennis."

____

AP Sports Writer John Pye contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-01-16-TEN-Australian-Open-Federer-Rift/id-ef06be504453452c8b9bea29974a84df

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